Corneal Esthesiometer Brill
The Corneal Esthesiometer Brill is an electronical device for corneal sensitivity assesment through controlled air pulses as stimuli. It is the first non-invasive and portable corenal esthesiometer.
Corneal EsthesiometerKey Features
Non invasive
Taking seamless key performance indicators offline to maximise the tail.
Portable
Nanotechnology immersion will close the loop on focusing solely on the bottom line.
Precise
Dramatically visualize customer directed convergence without revolutionary ROI.
Wireless
Assertively iterate resource maximizing products after leading intellectual capital.
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Key Mechanisms of DED
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CornealSensitivity
Corneal EsthesiometerIndications
The Corneal Esthesiometer Brill assesses the corneal sensitivity of the human eye. It is a decisive tool for detecting subclinical corneal dysesthesia and related pathologies, such as diabetic keratopathy or lesions in the fifth cranial nerve. Early diagnosis and early effective treatment of these pathologies can prevent the patient from losing their vision and quality of life.
By using the corneal esthesiometer, ophthalmologists can prescribe specific treatment at an early stage and can even evaluate the effectiveness of the treatment by assessing the patient’s corneal sensitivity.
The detection of corneal dysesthesia may indicate to optometrists that the patient needs to be referred to an ophthalmologist, making the Corneal Esthesiometer a functional instrument that can guide them in this matter.
Furthermore, the esthesiometer may be very helpful to optometrists during the contact lens adaptation process and for monitoring the loss of corneal sensitivity associated with overnight orthokeratology, as shown by recent studies 13, 14.
Precise
Dramatically visualize customer directed convergence without revolutionary ROI.
Non-Invasive
Nanotechnology immersion will close the loop on focusing solely on the bottom line.
Automated
Assertively iterate resource maximizing products after leading intellectual capital.
01Eye surgery
LASIK (laser-assisted in situ keratomileusis)3, LASEK (laser-assisted sub-epithelial keratomileusis)4 and corneal cross-linking5, among others. It has been suggested that the loss of corneal innervation resulting from these surgeries causes DED, loss of corneal sensitivity, and pain symptoms.
02Diabetic Keratopathy
Diabetic Keratopathy is characterized by abnormal innervation of the cornea, which results in decreased sensitivity and impaired epithelial wound healing6.
03Herpes Simplex Keratitis
Herpes Simplex Keratitis has been associated with more significant nerve damage. In the acute phase of this disease, loss of corneal sensation correlates strongly with a significant reduction in sub-basal nerve density7.
04Dry Eye Disease
DED begins with increasing nerve density and increased sensitivity (hyperesthesia) in the early stages, followed by a reduction in nerve density and hypoesthesia as the disease progresses8.
05Neurotrophic Keratopathy (NK)
Neurotrophic Keratopathy (NK) is a degenerative disease of the cornea caused by damage to the trigeminal nerve that causes loss of corneal sensitivity, the development of spontaneous lesions in the corneal epithelium, and the degradation of the healing capacity, which can lead to the development of ulcers, necrosis, and corneal perforation9.
06Keratoconus
Reduced corneal sensitivity in keratoconus is associated with age, disease duration, severity, lower central nerve fiber density, and the use of contact lenses10.
07Contact lens
Contact lens use is associated with reduced corneal sensitivity, although non-structural functional nerve changes related to this loss of corneal sensitivity have been demonstrated11.
08Fuchs’ endothelial corneal dystrophy (FECD)
Fuchs’ endothelial corneal dystrophy (FECD) has been linked to low sensitivity and nerve density, caused by corneal nerve changes in conditions associated with chronic corneal edema12.
Brill Engines, S.A. is a company created in 2019 dedicated to the development, registration, industrialization and placing on the market of new innovative products in the field of eye health world.
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